Everything about ceesdekker.net
Everything about ceesdekker.net
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Our group studies bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that will autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Handle.
Back in 1991, Sumio Iijima of your NEC Company experienced described the synthesis of carbon nanotubes. Band construction calculations suggested that these nanotubes could show metallic band conduction. This could be a significant benefit above the conducting polymers we had explored, which were, in fact, disordered semiconductors supplying just variable-selection hopping conductivity.
Considering that 2000, Dekker has shifted the main target of his get the job done towards biophysics in which he experiments the properties of single biomolecules and cells using the instruments of nanotechnology. This transformation of discipline was pushed by his fascination with the outstanding working of biological molecular constructions, and by the extended-expression point of view that numerous interesting discoveries may be anticipated In this particular subject.[five] Present-day strains of study in his biophysics group are within the areas of:[6]
This yielded a breakthrough. Within just only a few months, we were being capable of evaluate transport as a result of a person one-walled carbon nanotube. Depending on low-temperature experiments by an excellent PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft College of Engineering having an active exploration lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Microbiology has only existed to get a century, since we began to research micro-organisms extra severely. I thought nanobiology was an correct phrase, since all molecular biological pertinent interactions happen on the nanoscale: a protein is a number of nanometres in dimensions, DNA is two nm thick.’
We use nanofabricated microfluidic constructions to pattern spatial boundaries for microorganisms and biomimetic vesicles with reconstituted https://www.ceesdekker.net protein networks and this assess the elemental job of spatial confinement within the molecular and mobile stage. Our assignments incorporate the next:
He also identified time to jot down numerous guides, deliver Pretty much forty thousand tweets and lead A prosperous research group at Delft College of Technologies. ‘It doesn’t sense like function’, he claims. ‘I’m just terribly curious.’
Being familiar with essential procedures regulating the spatial and dynamic organisation of the DNA in live cells.
Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding given that the move-building system
Illustration (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in gray, the rim on the pore is highlighted in purple, plus a 3D rendering in the motion of your DNA rod is exhibited.
2001, discovery of one-electron transistors at home temperature based on nanotubes; realization of very first logic circuits with carbon nanotube units; and discovery with the molecular framework of DNA maintenance enzymes with AFM
2008, first observation of protein-coated DNA translocation via nanopores; resolved the origin of the electrophoretic force on DNA in nanopores; discovered an important velocity maximize of microtubules in electric powered fields; learned an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of noise in carbon nanotubes in liquid
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)